
Ovarian Cancer: Breaking the Silence on the "Silent Killer"
The Hidden Threat: Understanding Ovarian Cancer
It's often called the "silent killer" for good reason. Ovarian cancer typically develops quietly, with symptoms so subtle they're easily dismissed as everyday discomforts. By the time many women receive their diagnosis, the cancer has often advanced to later stages, making treatment more challenging.
As the 6th most common cancer among women in the UK, ovarian cancer deserves our attention—not our fear. Knowledge is power, and understanding this disease could save your life or the life of someone you love.
"I thought I was just bloated from stress and my diet," recalls Sarah, a 54-year-old ovarian cancer survivor. "I never imagined that the persistent fullness I felt could be something serious. If I had known the warning signs, I might have been diagnosed months earlier."
The Stark Reality of Early Detection
The difference between early and late detection of ovarian cancer is dramatic:
When caught early (Stage 1): Approximately 90% survival rate
When discovered in advanced stages: Survival rates drop significantly
Despite these statistics, there is currently no routine NHS screening program for ovarian cancer. This makes proactive testing particularly important for those at higher risk.
Who Should Consider Ovarian Cancer Screening?

While any woman can develop ovarian cancer, certain factors significantly increase your risk:
Age and Lifestyle Factors
Women aged 50+ (the risk increases with age)
Women aged 40+ with additional risk factors
Women who have never been pregnant
Women who started periods early or experienced late menopause
Medical History
History of endometriosis (inflammation of tissue similar to the uterine lining)
Polycystic ovary syndrome (PCOS)
Hormone replacement therapy (particularly estrogen-only formulations)
Previous breast cancer
Family and Genetic Factors
Family history of ovarian, breast, or colorectal cancer
Known BRCA1 or BRCA2 gene mutations (these can increase lifetime ovarian cancer risk to 40-60% compared to about 1.5% in the general population)
Lynch syndrome (hereditary non-polyposis colorectal cancer)
"After my mother was diagnosed with ovarian cancer at 62, I learned about our family's BRCA2 mutation," shares Emma, 45. "Regular screening has become part of my life now. It gives me peace of mind knowing that if anything develops, we'll catch it early."
Recognizing the Whispers: Symptoms to Watch For
The early symptoms of ovarian cancer can be vague and easily attributed to other conditions. This is why ovarian cancer is often diagnosed at later stages. Pay attention to these warning signs, especially if they persist for more than three weeks:
Common Symptoms
Persistent bloating that doesn't come and go
Feeling full quickly or loss of appetite
Pelvic or lower abdominal pain
Needing to urinate more urgently or frequently
Additional Symptoms
Unexplained weight loss
Fatigue
Changes in bowel habits (constipation or diarrhea)
Back pain
Remember: These symptoms don't necessarily mean you have ovarian cancer, but if they're new for you and persist for more than three weeks, it's important to consult your doctor.
"Looking back, the signs were there," says Jane, diagnosed at age 58. "I'd been feeling full after eating just a little, and my stomach was constantly bloated. I thought it was just age or digestive issues. Now I tell every woman I know: If something feels off with your body for more than a few weeks, get it checked."
Understanding Your Screening Options
Several screening and diagnostic tools can help detect ovarian cancer:
1. CA-125 Blood Test
This test measures the level of CA-125, a protein that is often elevated in women with ovarian cancer.
What you should know:
It's a simple blood test
Elevated levels can indicate ovarian cancer
CA-125 can also be elevated due to benign conditions like endometriosis, fibroids, or even during menstruation
It's most useful when tracked over time to detect changes
2. Transvaginal Ultrasound (TVUS)
This imaging test uses sound waves to look at the uterus, fallopian tubes, and ovaries by inserting a wand-like device into the vagina.
What you should know:
It can help identify masses or irregularities on the ovaries
It's often used alongside CA-125 for better accuracy
It cannot definitively determine if a mass is cancerous
The procedure is typically painless and takes about 15-30 minutes
3. Genetic Testing
For women with a family history of ovarian or breast cancer, genetic testing can identify mutations that increase cancer risk.
What you should know:
Tests for BRCA1, BRCA2, and other gene mutations
A positive result doesn't mean you'll develop cancer, but indicates higher risk
Results can help guide screening frequency and preventive options
Can have implications for family members' health as well
4. Risk-Reducing Options
For women at very high risk, particularly those with BRCA mutations, preventative surgery may be considered.
What you should know:
Removal of ovaries and fallopian tubes (bilateral salpingo-oophorectomy) can reduce ovarian cancer risk by 85-95%
The procedure causes immediate menopause in premenopausal women
It's typically considered after childbearing is complete
The decision should be made after thorough consultation with healthcare providers
The Life-Changing Benefits of Early Detection
Taking a proactive approach to ovarian cancer screening offers several significant benefits:
Dramatically Improved Survival Rates
The 5-year survival rate for early-stage ovarian cancer (Stage 1) is approximately 90%, compared to much lower rates for advanced stages.
Expanded Treatment Options
Early diagnosis typically means:
Less extensive surgery may be needed
Treatment may be less aggressive
Better quality of life during and after treatment
Potential for fertility-sparing options for younger women
Peace of Mind
Regular screening can provide reassurance, especially for those at higher risk.
Family Protection
If genetic testing reveals hereditary risk factors, family members can be informed and take appropriate screening or preventive measures.
"After my diagnosis and treatment, my sisters and daughters all got tested for the BRCA mutation that I carry," explains Linda, a 60-year-old survivor. "Two of them tested positive and now have regular screenings. My diagnosis potentially saved their lives too."
Taking Action: Your Screening Plan
While there is no one-size-fits-all approach to ovarian cancer screening, these general guidelines can help:
For Average-Risk Women:
Be aware of the symptoms
Report persistent symptoms to your doctor promptly
Consider an annual pelvic exam
For Moderate-Risk Women (family history but no known genetic mutations):
Consider CA-125 tests and transvaginal ultrasounds annually, starting at age 35 or 10 years before the earliest diagnosis in your family
Discuss your family history with your doctor
For High-Risk Women (BRCA mutations or strong family history):
Begin CA-125 testing and transvaginal ultrasounds every 6-12 months starting at age 30 (or earlier based on family history)
Consider risk-reducing surgery after completing childbearing
Consult with a gynecologic oncologist or genetic counselor
Comprehensive Support at UK Medicare Screening Clinic
At UK Medicare Screening Clinic, we understand that ovarian cancer screening is not just a medical procedure—it's peace of mind. Our comprehensive approach offers:
CA-125 blood tests with expert interpretation
High-resolution transvaginal ultrasounds performed by experienced technicians
Genetic testing for BRCA1, BRCA2, and other relevant mutations
Thorough risk assessment considering your personal and family medical history
Expert consultation to discuss your results and next steps
Ongoing monitoring for high-risk individuals
Compassionate care in a supportive environment
Our specialists stay current with the latest research and guidelines to ensure you receive the most up-to-date screening and risk assessment options.
Take Control of Your Health Today
Don't let ovarian cancer remain a silent threat in your life. Whether you're experiencing symptoms, have a family history of cancer, or simply want the reassurance of a thorough screening, taking action now could make all the difference.
Remember: Early detection dramatically improves outcomes. When caught at Stage 1, the five-year survival rate for ovarian cancer is around 90%. That number alone makes screening worth considering, especially for those at higher risk.
Book your comprehensive ovarian cancer screening at UK Medicare Screening Clinic today. Our expert team will help you understand your personal risk factors and recommend the most appropriate screening options for your unique situation.
Your health deserves to be a priority—and sometimes, being proactive can save your life.
Useful Resources
For additional information and support, we recommend:
Ovarian Cancer Action - Research, awareness, and support
Target Ovarian Cancer - Comprehensive resources and support
The Eve Appeal - Information about gynecological cancers